A grant in the amount of $50,000 was awarded to Dr. Bob Elliott of Diatranz in support of his next porcine islet cell transplantation trial. This next trial will use improved encapsulation devices, and as with his last trial, no immunosuppression will be used.
See the following abstracts for more information on this exciting research.
No evidence of infection with porcine endogenous retrovirus in recipients of encapsulated porcine islet xenografts.
Elliott RB, Escobar L, Garkavenko O, Croxson MC, Schroeder BA, McGregor M, Ferguson G, Beckman N, Ferguson S.
Islet cell transplantation for the treatment of diabetes mellitus.
Kendall WF Jr, Collins BH, Opara EC.
Increase in beta-cell mass in transplanted porcine neonatal pancreatic cell clusters is due to proliferation of beta-cells and differentiation of duct cells.
Trivedi N, Hollister-Lock J, Lopez-Avalos MD, O’Neil JJ, Keegan M, Bonner-Weir S, Weir GC.
In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized
poly(ethylene glycol) diacrylate membranes.
Cruise GM, Hegre OD, Lamberti FV, Hager SR, Hill R, Scharp DS, Hubbell JA.